Frontotemporal dementia strikes early, ordinarily during the 50s, sometimes as youthful as age 45. In contrast to Alzheimer’s, it doesn’t influence memory, rather attacking the parts of the cerebrum which control thinking, reasoning and emotions.
The first symptom is likely lost of interest forever and the well-being of others. An individual may overlook their spouse or children’s feelings, get uncharacteristically frustrated and state or do improper things -, for example, laugh at a funeral.
Far and away more terrible, they’ll likely have no clue they have changed.
“It’s a pretty devastating disease that impacts people in the prime of their lives,” said neurologist Kaitlin Casaletto, an assistant professor in the Memory and Aging Center at the University of California, San Francisco.
“It’s especially hard on family members who can see the changes in their loved one they often can’t see.”
Science has attempted to give interventions to support these patients. Presently, a new study examination study Wednesday proposes that lifestyle changes may help moderate the disease progression.
Casaletto and her partners followed the activity levels of 105 individuals with the inherited form of the disease, the first study to do as such in this populace. They discovered individuals who ranked most elevated in levels of mental and physical activity eased back their functional decay from the disease by half.
“This is an extremely important study providing the strongest evidence yet that lifestyle factors can positively impact brain health, not only for Alzheimer’s disease but frontotemporal lobar dementia as well,” said neurologist Dr. Richard Isaacson, director of the Alzheimer’s Prevention Clinic at Weill Cornell Medicine.
“The study is even more impactful in that patients had a gene that would cause dementia, but they were still able to impact cognitive decline by over 55%,” Isaacson said.
“It was a remarkable effect to see so early on,” Casaletto said. “If this were a drug, we would be giving it to all of our patients.”
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